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David A Calderwood Selected Research

Group II Malformations of Cortical Development

8/2012Filamin A controls matrix metalloproteinase activity and regulates cell invasion in human fibrosarcoma cells.
11/2009Filamins regulate cell spreading and initiation of cell migration.

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David A Calderwood Research Topics

Disease

7Neoplasms (Cancer)
01/2021 - 02/2004
4Central Nervous System Cavernous Hemangioma
11/2020 - 02/2014
2Melanoma (Melanoma, Malignant)
01/2021 - 01/2013
2Group II Malformations of Cortical Development
08/2012 - 11/2009
2Acute Promyelocytic Leukemia
09/2011 - 12/2008
2Leukemia
09/2011 - 12/2008
1Inborn Genetic Diseases (Disease, Hereditary)
10/2018
1Colorectal Neoplasms (Colorectal Cancer)
01/2016
1Nervous System Diseases (Neurological Disorders)
03/2015
1Seizures (Absence Seizure)
03/2015
1Hemorrhagic Stroke
03/2015
1Vascular Remodeling
01/2015
1Hypoxia (Hypoxemia)
01/2015
1Nephrotic Syndrome (Syndrome, Nephrotic)
03/2014
1Albuminuria
03/2014
1Cardiomyopathies (Cardiomyopathy)
12/2012
1Fibrosarcoma
08/2012
1Myeloid Leukemia (Leukemia, Myelocytic)
08/2011
1Periventricular Nodular Heterotopia
11/2009
1Neoplasm Metastasis (Metastasis)
09/2006
1Inflammation (Inflammations)
09/2006
1Poikiloderma of Kindler
02/2004

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
11/2020 - 02/2004
6IntegrinsIBA
03/2015 - 02/2004
3FilaminsIBA
08/2012 - 12/2008
3Tretinoin (Retinoic Acid)FDA LinkGeneric
09/2011 - 12/2008
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2021
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
01/2021
1Actins (F Actin)IBA
10/2018
1CalponinsIBA
10/2018
1A-factor (Streptomyces)IBA
01/2016
1Small Interfering RNA (siRNA)IBA
01/2016
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
03/2015
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2015
1CalpainIBA
03/2014
1Laminin (Merosin)IBA
03/2014
1LigandsIBA
03/2014
1Peptides (Polypeptides)IBA
01/2013
1Matrix Metalloproteinases (MMPs)IBA
08/2012
1Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
09/2011
1Oncogene Proteins (Oncogene Protein)IBA
09/2011
1Protein Isoforms (Isoforms)IBA
09/2011
1Biological ProductsIBA
11/2009
1CytokinesIBA
12/2008
1Metalloproteases (Metalloproteinases)IBA
09/2006
1Peptide Hydrolases (Proteases)FDA Link
09/2006
1DisintegrinsIBA
09/2006
1Transforming Growth Factor beta (TGF-beta)IBA
02/2004
1Transforming Growth Factor beta1 (TGF beta 1)IBA
02/2004

Therapy/Procedure

2Therapeutics
01/2021 - 01/2016